<임상 연구>

1.MET 유전자 양성 고형암 신약 임상 치료
2.FGFR2 양성 담도암 신약 임상 치료
3.2~3기 악성 흑색종 면역치료요법 임상 연구
4.TSC 유전자 양성 고형암 신약 임상 치료
5.MIBC (침윤성 방광암) 면역항암제 연구
6.RAS Q61X 돌연변이 표적항암제 연구
7.HER2 양성 담도암에서 Nivolumab / trastuzumab / 항암제 적용 연구
8.KRAS G12C 폐암 / 대장암 표적치료제 연구

<논문>

A Phase II Study to Compare the Safety and Efficacy of Direct Oral Anticoagulants versus Subcutaneous Dalteparin for Cancer-Associated Venous Thromboembolism in Patients with Advanced Upper Gastrointestinal, Hepatobiliary and Pancreatic Cancer: PRIORITY
Cancers 2022, 14(3), 559

Synergism of a novel MCL 1 downregulator, acriflavine, with navitoclax (ABT 263) in triple negative breast cancer, lung adenocarcinoma and glioblastoma multiforme
INTERNATIONAL JOURNAL OF ONCOLOGY January-2022 Volume 60 Issue 1

Long-Term Outcomes in Patients With Advanced and/or Metastatic Non?Small Cell Lung Cancer Who Completed 2 Years of Immune Checkpoint Inhibitors or Achieved a Durable Response After Discontinuation Without Disease Progression: Multicenter, Real-World Data (KCSG LU20-11)
Cancer Volume128, Issue4 February 15, 2022

Glymphatic system function in patients with newly diagnosed focal epilepsy
March 2022 Brain and Behavior 12(3)

The effects of direct hemoperfusion with polymyxin B-immobilized fiber in patients with acute exacerbation of interstitial lung disease
Acute and Critical Care 2021 May 36(2):126-132

Liposomal irinotecan plus fluorouracil and leucovorin versus fluorouracil and leucovorin for metastatic biliary tract cancer after progression on gemcitabine plus cisplatin (NIFTY): a multicentre, open-label, randomised, phase 2b study
LANCET ONCOLOGY Volume 22, ISSUE 11, P1560-1572, November 01, 2021

Induction of Triple-negative Breast Cancer Cells to Immunogenic Cell Death and Increase Cross-Presentation by Streptomyces sanyensis
Pharmacognosy Research. Jul-Sep2021, Vol. 13 Issue 3, p165-172. 8p.

Implantable ascites drainage stent designs and experiments to improve the quality of life in terminal cancer patients
Journal of Advanced Marine Engineering and Technology - Vol. 45, No. 5, p.269-274

Liposomal irinotecan plus fluorouracil/leucovorin versus FOLFIRINOX as the second-line chemotherapy for patients with metastatic pancreatic cancer: a multicenter retrospective study of the Korean Cancer Study Group (KCSG)
ESMO OPEN Volume 6, ISSUE 2, 100049, April 01, 2021

Combined treatment with anti HER2/neu and anti 4 1BB monoclonal antibodies induces a synergistic antitumor efect but requires dose optimization to maintain immune memory for protection from lethal rechallenge
Cancer Immunology, Immunotherapy 71(1):1-12 January 2022

Efficacy and safety of atezolizumab plus bevacizumab in Korean patients with advanced hepatocellular carcinoma
Liver International. Volume42, Issue3March 2022 P.674-681

Are there network differences between the ipsilateral and contralateral hemispheres of pain in patients with migraine?
Research square 2021

Alterations of the intrinsic amygdala-hippocampal network in juvenile myoclonic epilepsy
Brain Behavior Volume11, Issue8 August 2021

Design of a Machine Learning-Assisted Wearable Accelerometer-Based Automated System for Studying the Effect of Dopaminergic Medicine on Gait Characteristics of Parkinson’s Patients
Journal of Healthcare Engineering Volume 2020, Article ID 1823268, 2040-2295; 2040-2309, 2020-02

Efficacy and safety of second-line nabpaclitaxel plus gemcitabine after progression on FOLFIRINOX for unresectable or metastatic pancreatic ductal adenocarcinoma: multicenter retrospective analysis
Therapeutic advances in medical oncology 2020 May , Vol. 12: 1? 8

Enlightening the immune mechanism of the abscopal effect in a murine HCC model and overcoming the late resistance with anti PD-L1i
International Journal of Radiation Oncology, Biology, Physics, 29 Dec 2020, 110(2):510-520

Regorafenib in patients with advanced Child-Pugh B hepatocellular carcinoma: A multicentre retrospective study.
Liver International. 2020 Vol.40 Issue 10 :2544-2552

Regorafenib in previously treated advanced hepatocellular carcinoma: Impact of prior immunotherapy and adverse events
Liver International Vol.40 Issue 10 , 2544-2552, 1 Oct 2020

Top 100 Cited Articles on Sleep Medicine : A Bibliometric Analysis
Eur Neurol 2020;83:111?119

Top 100 Cited Articles on Peritoneal Dialysis: A Bibliometric Analysis
The Open Urology & Nephrology Journal, 2020, 13, 39-47

Differences of connectivity between ESRD patients with PD and HD
Brain and Behavior 2020 Aug; Vol.10(8)

Atypical Hemolytic Uremic Syndrome (p.Gly1110Ala) with Autoimmune Disease
Am J Case Rep, 2020 Vol.21

Analysis of the risk factors of acute kidney injury after total hip or knee replacement surgery
Yeungnam University Journal of Medicine 2021;38(2):136-141

Alterations in Structural and Functional Connectivities in Patients with End-Stage Renal Disease
J Clin Neurol 2020;16(3):390-400

Serum S100B represents a biomarker for cognitive impairment in patients with end-stage renal disease
Clinical Neurology and Neurosurgery Volume 195, August 2020

Clinical characteristics of clear cell ovarian cancer : a retrosepctive multicenter experience of 308 patients in south korea
Cancer Research and Treatment 2020; 52(1): 277-283

Real-world efficacy and safety of liposomal irinotecan plus fluorouracil/leucovorin in patients with metastatic pancreatic adenocarcinoma: a study by the Korean Cancer Study Group.
Ther Adv Med Oncol. v.11; 2019

A PI3K p110-selective inhibitor enhances the efficacy of anti-HER2/neu antibody therapy against breast cancer in mice
Onco-Immunology Article v.7(5); 2018

Synchronous Hepatocellular Carcinoma and B-Cell Non-Hodgkin’s Lymphoma in Chronic Hepatitis C Patient
Korean J Gastroenterol 2014 Vol. 64 No. 3, 168-172

Alterations of brain network hubs in reflex syncope: Evidence from a graph theoretical analysis based on DTI
Brain and Behavior Volume8, Issue6 June 2018

A Case of Seizure Revealing Fahr’s Syndrome with Primary Hypoparathyroidism
Am J Case Rep, 2018; 19: 1430-1433

Basiliximab-Induced Non-Cardiogenic Pulmonary Edema in a Kidney Transplant Patient
J Korean Soc Transplant 2018;32:63-68

Rhabdomyolysis with Peripheral Neuropathy : A Case Series and Literature Review
Am J Case Rep, 2018; 19: 1272-1278

Snail maintains metastatic potential, cancer stemlike properties, and chemoresistance in mesenchymal mouse breast cancer TUBO P2J cells
ONCOLOGY REPORTS 38(3) : 1867-1876, 2017

Pulmonary Artery Sarcoma ? Multimodality Imaging
Journal of Clinical Imaging Science. Vol. 6. Issue 4. Oct Dec 2016

Efficacy and safety of deferasirox estimated by serum ferritin and labile plasma iron levels in patients with aplastic anemia, myelodysplastic syndrome, or acute myeloid leukemia with transfusional iron overload.
Transfusion. Volume55, Issue7 July 2015 Pages 1613-1620

Expression of carbonic anhydrase 9 is a novel prognostic marker in resectable hepatocellular carcinoma.
Virchows Arch. 2015 Apr;466(4):403-13

Alterations of gray matter volumes and connectivity in patients with tuberous sclerosis complex.
JOURNAL OF CLINICAL NEUROSCIENCE Volume 72, February 2020, Pages 360-364

Clinical Characteristics of Clear Cell Ovarian Cancer: A Retrospective Multicenter Experience of 308 Patients in South Korea.
Cancer Research and Treatment Volume 52(1); 2020

Therapeutic strategy for in-stent restenosis based on the restenosis pattern after drug-eluting stent implantation.
Korean Circ J. 2009 Oct;39(10):408-13

Comparison of Triple Anti-Platelet Therapy (Aspirin, Clopidogrel, and Cilostazol) and Double Anti-Platelet Therapy (Aspirin and Clopidogrel) on Platelet Aggregation in Type 2 Diabetic Patients Undergoing Drug-Eluting Stent Implantation
Korean Circ J. 2009 Nov;39(11):462-6